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Multalin version 5.4.1
Copyright I.N.R.A. France 1989, 1991, 1994, 1996
Published research using this software should cite
Multiple sequence alignment with hierarchical clustering
F. CORPET, 1988, Nucl. Acids Res., 16 (22), 10881-10890
Symbol comparison table: blosum62
Gap weight: 12
Gap length weight: 2
Consensus levels: high=90% low=50%
Consensus symbols:
! is anyone of IV
$ is anyone of LM
% is anyone of FY
# is anyone of NDQEBZ
MSF: 791 Check: 0 ..
Name: CPT1_HUMAN Len: 791 Check: 4088 Weight: 1.07
Name: CPTM_HUMAN Len: 791 Check: 1694 Weight: 1.07
Name: CPT1-1_DROME Len: 791 Check: 1132 Weight: 0.93
Name: CPT1-2_DROME Len: 791 Check: 8314 Weight: 0.93
Name: Consensus Len: 791 Check: 2492 Weight: 0.00
//
1 60
CPT1_HUMAN MAEAHQAVAF QFTVTPDGID LRLSHEALRQ IYLSGLHSWK KKFIRFKNGI ITGVYPASPS
CPTM_HUMAN MAEAHQAVAF QFTVTPDGVD FRLSREALKH VYLSGINSWK KRLIRIKNGI LRGVYPGSPT
CPT1-1_DRO MAEAHAAVAF SFAITHEGFD INYDHEVLNL VWNSGVRSWK KRLARARNGV RNGVYPAHIQ
CPT1-2_DRO MAEAHAAVAF SFAITHEGFD INYDHEVLNL VWNSGVRSWK KRLARARNGV RNGVYPAHIQ
Consensus MAEAHqAVAF qFt!Tp#G.D .rlshEaL.. !ylSG..SWK KrliR.kNG! ..GVYPasp.
61 120
CPT1_HUMAN SWLIVVVGVM TTMYAKIDPS LGIIAKINRT LETA--NCMS SQTKNVVSGV LFGTGLWVAL
CPTM_HUMAN SWLVVIMATV GSSFCNVDIS LGLVSCIQRC LPQGCGPYQT PQTRALLSMA IFSTGVWVTG
CPT1-1_DRO SLWLISAIAL GLHFAGYQAP FNLTNRILVH LPSNTINWQ- -----VTACF LAALVVWLSI
CPT1-2_DRO SLWLISAIAL GLHFAGYQAP FNLTNRILVH LPSNTINWQ- -----VTACF LAALVVWLSI
Consensus Swl.!..... g..%a..#.s lgl...I.r. Lp....n.q. .qt..v.s.. lf.tgvWv..
121 180
CPT1_HUMAN IVTMRYSLKV LLSYHGWMFT EHGKMSRA-- -TKIWMGMVK IFSG-RKPML YSFQTSLPRL
CPTM_HUMAN IFFFRQTLKL LLCYHGWMFE MHGKTSNL-- -TRIWAMCIR LLSS-RHPML YSFQTSLPKL
CPT1-1_DRO CFTMRYTLKL LLMYKGWMYE SRAPGSRVSL PTMLWVAVVR VLSSWNKPGL YSFQGSLPRL
CPT1-2_DRO CFTMRYTLKL LLMYKGWMYE SRAPGSRVSL PTMLWVAVVR VLSSWNKPGL YSFQGSLPRL
Consensus iftmRytLKl LL.YhGWM%e .hgk.Sr... .T.iW...!r .lSs.rkPmL YSFQtSLPrL
181 240
CPT1_HUMAN PVPAVKDTVN RYLQSVRPLM KEEDFKRMTA LAQDFAVGLG PRLQWYLKLK SWWATNYVSD
CPTM_HUMAN PVPRVSATIQ RYLESVRPLL DDEEYYRMEL LAKEFQDKTA PRLQKYLVLK SWWASNYVSD
CPT1-1_DRO PLPSVKDTMT RYLRSVRPLL DDENYTRMER LAKEFEQTIG KKLQWYLILK SWWSTNYVSD
CPT1-2_DRO PLPSVKDTMT RYLRSVRPLL DDENYTRMER LAKEFEQTIG KKLQWYLILK SWWSTNYVSD
Consensus PvP.VkdT.. RYL.SVRPL$ d#E#%.RMe. LAk#F....g prLQwYL.LK SWWatNYVSD
241 300
CPT1_HUMAN WWEEYIYLRG RGPLMVNSNY YAMDLLYILP THIQAARAGN AIHAILLYRR KLDREEIKPI
CPTM_HUMAN WWEEYIYLRG RSPLMVNSNY YVMDLVLIKN TDVQAARLGN IIHAMIMYRR KLDREEIKPV
CPT1-1_DRO WWEEYVYLRG RSPLCVNSNF YGTDAIFMNL TDKQAARAAN VISLLLNFRR LIEHQELQPI
CPT1-2_DRO WWEEYVYLRG RSPLCVNSNF YGTDAIFMNL TDKQAARAAN VISLLLNFRR LIEHQELQPI
Consensus WWEEY!YLRG RsPLmVNSN% Y.mDl..i.. Td.QAARagN .Iha.l.%RR kl#r#EikP!
301 360
CPT1_HUMAN RLLGSTIPLC SAQWERMFNT SRIPGEETDT IQHMRDSKHI VVYHRGRYFK VWLYHDGRLL
CPTM_HUMAN MALG-IVPMC SYQMERMFNT TRIPGKDTDV LQHLSDSRHV AVYHKGRFFK LWLYEGARLL
CPT1-1_DRO MVQG-MIPLC SWQYERTFNT ARVPGLETDR IIHYRDSNHI VVLHKGCYYK MLIYYKGRIL
CPT1-2_DRO MVQG-MIPLC SWQYERTFNT ARVPGLETDR IIHYRDSNHI VVLHKGCYYK MLIYYKGRIL
Consensus m.lG..!P$C S.Q.ERmFNT .R!PG.#TD. iqH.rDS.H! vVyHkGr%%K .wlY..gRlL
361 420
CPT1_HUMAN KPREMEQQMQ RILDNTSEPQ PGEARLAALT AGDRVPWARC RQAYFGRGKN KQSLDAVEKA
CPTM_HUMAN KPQDLEMQFQ RILDDPSPPQ PGEEKLAALT AGGRVEWAQA RQAFFSSGKN KAALEAIERA
CPT1-1_DRO RPCELQVQIE EILKGKATPV EGEEHLAALT AWNRSKWAEA RNTFFSWGVN QTSLRTIESA
CPT1-2_DRO RPCELQVQIE EILKGKATPV EGEEHLAALT AWNRSKWAEA RNTFFSWGVN QTSLRTIESA
Consensus kP.#$#.Q.# rILd..s.Pq pGEe.LAALT Ag.Rv.WA.a R#a%Fs.GkN k.sL.a!E.A
421 480
CPT1_HUMAN AFFVTLDETE EGYRSEDPDT SMDSYAKSLL HGRCYDRWFD KSFTFVVFKN GKMGLNAEHS
CPTM_HUMAN AFFVALDEES YSYDPED-EA SLSLYGKALL HGNCYNRWFD KSFTLISFKN GQLGLNAEHA
CPT1-1_DRO AFVLSLDDEP FEFDLARPEL -LDNFGKKLL HGNGYNRWFD KCFTVCVGTN GRVGFNAEHT
CPT1-2_DRO AFVLSLDDEP FEFDLARPEL -LDNFGKKLL HGNGYNRWFD KCFTVCVGTN GRVGFNAEHT
Consensus AFfv.LD#e. ..%d.edp#. s$d.%gK.LL HGncY#RWFD KsFT..vfkN G..GlNAEH.
481 540
CPT1_HUMAN WADAQIVAHL WEYVMSIDSL QLGYAEDGHC KGDINPNIPY PTRLQWDIPG ECQEVIETSL
CPTM_HUMAN WADAPIIGHL WEFVLGTDSF HLGYTETGHC LGKPNPALAP PTRLQWDIPK QCQAVIESSY
CPT1-1_DRO WSDAAIASHM WENLIVDDLV SDGYDETGNT KGTPAFQPPT PTRLTWDL-K PCLAQIEEAT
CPT1-2_DRO WADAPVLGHL WEYIFGDDIY --GYDETGNT KGTPAFQPPT PTRLTWDL-K PCLAQIEEAT
Consensus WaDAp!.gH$ WEyv.g.Ds. .lGY.EtGhc kG.pnp..p. PTRLqWDipk .CqavIE.s.
541 600
CPT1_HUMAN NTANLLANDV DFHSFPFVAF GKGIIKKCRT SPDTFVQLAL QLAHYKDMGK FCLTYEASMT
CPTM_HUMAN QVAKALADDV ELYCFQFLPF GKGLIKKCRT SPDAFVQIAL QLAHFRDRGK FCLTYEASMT
CPT1-1_DRO IDVTKLINEV NLRILVHQDY GKGFMKKCRI SPDAYIQMAL QLAYYRDAGR FSLTYEASMT
CPT1-2_DRO IDVTKLINEV NLRILVHQDY GKGFMKKCRI SPDAYIQMAL QLAYYRDAGR FSLTYEASMT
Consensus ..a..La##V #l..f.f..% GKG.iKKCRt SPDa%!Q.AL QLAh%rD.Gk FcLTYEASMT
601 660
CPT1_HUMAN RLFREGRTET VRSCTTESCD FVRAMVDPAQ TVEQRLKLFK LASEKHQHMY RLAMTGSGID
CPTM_HUMAN RMFREGRTET VRSCTSESTA FVQAMMEGSH TKADLRDLFQ KAAKKHQNMY RLAMTGAGID
CPT1-1_DRO RLFREGRTET VRPCTIESSA WVKAMQNPNT TNDERVKMMQ AACDRHQLGY QDAMCGRGID
CPT1-2_DRO RLFREGRTET VRPCTIESSA WVKAMQNPNT TNDERVKMMQ AACDRHQLGY QDAMCGRGID
Consensus R$FREGRTET VRsCT.ES.a fV.AM.#p.. T..#r.k$fq .A..kHQ.mY rlAMtG.GID
661 720
CPT1_HUMAN RHLFCLYVVS KYLAVESPFL KEVLSEPWRL STSQTPQQQV ELFDLENNPE YVSSGGGFGP
CPTM_HUMAN RHLFCLYLVS KYLGVSSPFL AEVLSEPWRL STSQIPQSQI RMFDPEQHPN HLGAGGGFGP
CPT1-1_DRO RHLFCLYVVS KYLEVDSPFL NEVLSEPWRL STSQTPHGQT PKMDLKKHPN CISAGGGFGP
CPT1-2_DRO RHLFCLYVVS KYLEVDSPFL NEVLSEPWRL STSQTPHGQT PKMDLKKHPN CISAGGGFGP
Consensus RHLFCLYvVS KYL.V.SPFL .EVLSEPWRL STSQtPq.Q. ..fDle.hP# ..saGGGFGP
721 780
CPT1_HUMAN VADDGYGVSY ILVGENLINF HISSKFSCPE TDSHRFGRHL KEAMTDIITL FGLSSNSKK
CPTM_HUMAN VADDGYGVSY MIAGENTIFF HISSKFSSSE TNAQRFGNHI RKALLDIADL FQVPKAYS
CPT1-1_DRO VADDGYGVSY IIAGENLIFF HISAKTTCQQ TDVHRFAQNI SQALSDIRSM FEQHMKDHPK
CPT1-2_DRO VADDGYGVSY IIAGENLIFF HISAKTTCQQ TDVHRFAQNI SQALSDIRSM FEQHMKDHPK
Consensus VADDGYGVSY iiaGENlIfF HISsKfsc.# T#.hRFg.hi ..A$.DI..$ F.........
781 791
CPT1_HUMAN
CPTM_HUMAN
CPT1-1_DRO PAKSLTNGKS T
CPT1-2_DRO PAKSLTNGKS T
Consensus .......... .